Enhanced Expression of Interleukin-8 and Activation of Nuclear Factor Kappa-B in Endoscopy-negative Gastroesophageal Reflux Disease

200484 citationsJournal Article

Authors

Hajime Isomoto · Inoue Hospital

Vladimir Saenko

Abstract

Our results demonstrate enhanced mucosal expression of IL-8 in incipient GERD even without mucosal breaks. NF-kappaB activation may be implicated in the pathogenesis in GERD.

Topics & Keywords

Gastroesophageal reflux and treatments Eosinophilic Esophagitis Helicobacter pylori-related gastroenterology studies

Publication Details

Published in: The American Journal of Gastroenterology

Volume 99, Issue 4, pp. 589-597

DOI: 10.1111/j.1572-0241.2004.04110.x

Field-Weighted Citation Impact: 2.25

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Enhanced Expression of Interleukin-8 and Activation of Nuclear Factor Kappa-B in Endoscopy-negative Gastroesophageal Reflux Disease

Authors

Abstract

Topics & Keywords

Publication Details