Emergence of Azole Resistance in Aspergillus fumigatus and Spread of a Single Resistance Mechanism

2008713 citationsJournal Articlegold Open Access

Authors

Eveline Snelders · Radboud University Nijmegen

Henrich A. L. van der Lee · Institute of Infection and Immunity

Judith Kuijpers · Radboud University Nijmegen

Anthonius J. M. M. Rijs · Radboud University Nijmegen

János Varga · Westerdijk Fungal Biodiversity Institute

Robert A. Samson · Westerdijk Fungal Biodiversity Institute

Emilia Mellado

Abstract

Azole resistance has emerged in A. fumigatus and might be more prevalent than currently acknowledged. The presence of a dominant resistance mechanism in clinical isolates suggests that isolates with this mechanism are spreading in our environment.

Topics & Keywords

Antifungal resistance and susceptibility Fungal Infections and Studies Plant Pathogens and Fungal Diseases

UN Sustainable Development Goals

Partnerships for the goals

Publication Details

Published in: PLoS Medicine

Volume 5, Issue 11, pp. e219-e219

DOI: 10.1371/journal.pmed.0050219

Field-Weighted Citation Impact: 21.07