A Novel System for Transcutaneous Application of Carbon Dioxide Causing an “Artificial Bohr Effect” in the Human Body

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Authors

Yoshitada Sakai · Kobe University

Masahiko Miwa · Kobe University

Keisuke Oe · Kobe University

Takeshi Ueha · NeoChemir (Japan)

Akihiro Koh · Kobe University

Takahiro Niikura · Kobe University

Takashi Iwakura · Kobe University

Abstract

Our novel transcutaneous CO(2) application facilitated an O(2) dissociation from Hb in the human body, thus providing evidence of the Bohr effect in vivo.

Topics & Keywords

Optical Imaging and Spectroscopy Techniques Traumatic Brain Injury and Neurovascular Disturbances Cerebrospinal fluid and hydrocephalus

UN Sustainable Development Goals

Clean water and sanitation

Publication Details

Published in: PLoS ONE

Volume 6, Issue 9, pp. e24137-e24137

DOI: 10.1371/journal.pone.0024137

Field-Weighted Citation Impact: 2.03