Intranasal Mupirocin to Prevent Postoperative<i>Staphylococcus aureus</i>Infections

2002794 citationsJournal Articlebronze Open Access

Authors

Trish M. Perl · University of Iowa

Joseph J. Cullen · University of Iowa

Richard P. Wenzel · American Association of Colleges of Pharmacy

M. Bridget Zimmerman · American Association of Colleges of Pharmacy

Michael A. Pfaller · University of Iowa

Deborah Sheppard · University of Iowa

Jennifer Twombley

Abstract

Prophylactic intranasal application of mupirocin did not significantly reduce the rate of S. aureus surgical-site infections overall, but it did significantly decrease the rate of all nosocomial S. aureus infections among the patients who were S. aureus carriers.

Topics & Keywords

Antimicrobial Resistance in Staphylococcus Sinusitis and nasal conditions Otolaryngology and Infectious Diseases

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 346, Issue 24, pp. 1871-1877

DOI: 10.1056/nejmoa003069

Field-Weighted Citation Impact: 18.25