Desmoplastic Reaction in Pancreatic Cancer

2004584 citationsJournal Article

Authors

Minoti V. Apte · Bankstown Lidcombe Hospital

S. Park · Bankstown Lidcombe Hospital

Phoebe A. Phillips · Bankstown Lidcombe Hospital

Nicole Santucci · Bankstown Lidcombe Hospital

David Goldstein · UNSW Sydney

Rakesh Kumar · UNSW Sydney

Grant A. Ramm ·

Abstract

Activated PSCs are present in the stromal reaction in pancreatic cancers and are responsible for the production of stromal collagen. PSC function is influenced by pancreatic cancer cells. Interactions between tumor cells and stromal cells (PSCs) may play an important role in the pathobiology of pancreatic cancer.

Topics & Keywords

Pancreatic and Hepatic Oncology Research Bone and Dental Protein Studies Cancer Cells and Metastasis

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Pancreas

Volume 29, Issue 3, pp. 179-187

DOI: 10.1097/00006676-200410000-00002

Field-Weighted Citation Impact: 2.66