Seizures and transient cortical blindness associated with cis-platinum (II) diamminedichloride (PDD) therapy in a thirty-year-old man

Cis-Platinum is a phase II chemotherapeutic agent effective against a variety of tumors. Known toxic effects include gastrointestinal, renal, audiologic, and hematologic as well as idiosyncratic and atopic. A 30-year-old male who was treated with cis-Platinum diamminedichloride II for disseminated embryonal cell carcinoma of the testicle developed seizures and cortical blindness.