An inherited NBN mutation is associated with poor prognosis prostate cancer

201298 citationsJournal Articlehybrid Open Access

Authors

Cezary Cybulski · International Hereditary Cancer Center

Dominika Wokołorczyk · International Hereditary Cancer Center

Wojciech Kluźniak · International Hereditary Cancer Center

Anna Jakubowska · International Hereditary Cancer Center

Bohdan Górski · International Hereditary Cancer Center

Jacek Gronwald · International Hereditary Cancer Center

Tomasz Huzarski

Abstract

A mutation in NBS1 predisposes to aggressive prostate cancer. These data are relevant to the prospect of adapting personalised medicine to prostate cancer prevention and treatment.

Topics & Keywords

BRCA gene mutations in cancer DNA Repair Mechanisms Genetic factors in colorectal cancer

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: British Journal of Cancer

Volume 108, Issue 2, pp. 461-468

DOI: 10.1038/bjc.2012.486

Field-Weighted Citation Impact: 3.31