Association between laminin‐8 and glial tumor grade, recurrence, and patient survival

200471 citationsJournal Articlebronze Open Access

Authors

Julia Y. Ljubimova · Cedars-Sinai Medical Center

M. S. Fugita · Cedars-Sinai Medical Center

Natalya M. Khazenzon · Cedars-Sinai Medical Center

Asha Das · Cedars-Sinai Medical Center

Brian B. Pikul · Cedars-Sinai Medical Center

Daniel M. Newman · Cedars-Sinai Medical Center

Kiyotoshi Sekiguchi

Abstract

The data suggest that laminin-8, which may facilitate tumor invasion, contributes to tumor regrowth after therapy. Laminin-8 may be used as a predictor of tumor recurrence and patient survival and as a potential molecular target for glioma therapy.

Topics & Keywords

Cell Adhesion Molecules Research Caveolin-1 and cellular processes Proteoglycans and glycosaminoglycans research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Cancer

Volume 101, Issue 3, pp. 604-612

DOI: 10.1002/cncr.20397

Field-Weighted Citation Impact: 2.18