Improvement in fetal DNA extraction from maternal plasma. Evaluation of the NucliSens Magnetic Extraction system and the QIAamp DSP Virus Kit in comparison with the QIAamp DNA Blood Mini Kit

200663 citationsJournal Article

Authors

Frederik Banch Clausen · Copenhagen University Hospital

Grethe Risum Krog · Copenhagen University Hospital

Klaus Rieneck · Copenhagen University Hospital

Morten Hanefeld Dziegiel · Copenhagen University Hospital

Abstract

Both extraction systems tested were superior to our standard with regard to DNA yield. This improvement may have a great impact on the success of genotyping in early pregnancy.

Topics & Keywords

Prenatal Screening and Diagnostics Parvovirus B19 Infection Studies Fetal and Pediatric Neurological Disorders

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Prenatal Diagnosis

Volume 27, Issue 1, pp. 6-10

DOI: 10.1002/pd.1605

Field-Weighted Citation Impact: 4.58