Clinical and Genetic Heterogeneity of Right Bundle Branch Block and ST-Segment Elevation Syndrome

2000455 citationsJournal Articlebronze Open Access

Authors

Silvia G. Priori · IRCCS Ospedale San Raffaele

Carlo Napolitano · Azienda di Rilievo Nazionale ed Alta Specializzazione

Maurizio Gasparini · IRCCS Ospedale San Raffaele

Carlo Pappone · Azienda di Rilievo Nazionale ed Alta Specializzazione

Paolo Della Bella · Azienda Unità Sanitaria Locale Della Romagna

Michele Brignole · IRCCS Ospedale San Raffaele

Umberto Giordano

Abstract

At variance with current views, asymptomatic patients are at lower risk for sudden death. Programmed electrical stimulation identifies only a fraction of individuals at risk, and sodium channel blockade fails to unmask most silent gene carriers. This novel evidence mandates a reappraisal of therapeutic management.

Topics & Keywords

Cardiac electrophysiology and arrhythmias Cardiac pacing and defibrillation studies Ion channel regulation and function

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Circulation

Volume 102, Issue 20, pp. 2509-2515

DOI: 10.1161/01.cir.102.20.2509

Field-Weighted Citation Impact: 19.39