LuCaP 35: A new model of prostate cancer progression to androgen independence

2003155 citationsJournal Article

Authors

Eva Corey · University of Washington

Janna E. Quinn · University of Washington

Kent R. Buhler · University of Washington

Peter S. Nelson · Fred Hutch Cancer Center

Jill A. Macoska · Michigan Center for Translational Pathology

Lawrence D. True · University of Washington

Robert L. Vessella

Abstract

The availability of hormone-dependent and -independent variants of LuCaP 35, which exhibit many properties analogous to those of CaP in man, provides an excellent model system to study the processes associated with development of androgen independence and to evaluate new treatment modalities.

Topics & Keywords

Prostate Cancer Treatment and Research RNA and protein synthesis mechanisms RNA Research and Splicing

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: The Prostate

Volume 55, Issue 4, pp. 239-246

DOI: 10.1002/pros.10198

Field-Weighted Citation Impact: 7.81