Characteristics and Concordance of Autism Spectrum Disorders Among 277 Twin Pairs

2009476 citationsJournal Article

Authors

Rebecca E. Rosenberg · Kennedy Krieger Institute

Kiely Law · Kennedy Krieger Institute

Gayane Yenokyan · Johns Hopkins University

John McGready · Johns Hopkins University

Walter E. Kaufmann · Cancer Research And Biostatistics

Paul A. Law · Johns Hopkins University

Abstract

Our data support greater ASD concordance in MZ vs DZ twins. Overall higher functioning, psychiatric comorbidity, and Asperger syndrome concordance among affected MZ vs DZ twins may also suggest differential heritability for different ASDs. For families in which one MZ twin is diagnosed with ASD, the second twin is unlikely to receive an ASD diagnosis after 12 months. In addition, Internet parent report of ASD status is valid.

Topics & Keywords

Autism Spectrum Disorder Research Genetics and Neurodevelopmental Disorders Child Development and Digital Technology

UN Sustainable Development Goals

Quality Education

Publication Details

Published in: Archives of Pediatrics and Adolescent Medicine

Volume 163, Issue 10, pp. 907-907

DOI: 10.1001/archpediatrics.2009.98

Field-Weighted Citation Impact: 10.21