The Human Plasma Lipidome

2011447 citationsReviewgreen Open Access

Authors

Oswald Quehenberger · University of California San Diego

Edward A. Dennis · University of California San Diego

Abstract

Biochemical analyses reveal that plasma contains over 600 structural forms of lipid molecules. This review summarizes known correlations between levels of lipid moieties and disease and describes potential therapeutic targets relevant to CVD, cancer, and neurologic disease.

Topics & Keywords

Lipid metabolism and biosynthesis Sphingolipid Metabolism and Signaling Liver Disease Diagnosis and Treatment

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 365, Issue 19, pp. 1812-1823

DOI: 10.1056/nejmra1104901

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