Troglitazone Improves Psoriasis and Normalizes Models of Proliferative Skin Disease

2000209 citationsJournal Article

Authors

Charles N. Ellis

James Varani

Gary J. Fisher

Mary E. Zeigler · University of Michigan–Ann Arbor

Harrihar A. Pershadsingh · Kern Medical Center

Stephen C. Benson · California State University System

Yiqing Chi · University of Michigan–Ann Arbor

Theodore W. Kurtz · University of California, San Francisco

Abstract

Peroxisome proliferator-activated receptor-gamma might be a useful intracellular target for the treatment of psoriasis; further study is needed to assess the clinical value of ligands for PPARgamma, including troglitazone.

Topics & Keywords

Retinoids in leukemia and cellular processes Psoriasis: Treatment and Pathogenesis Peroxisome Proliferator-Activated Receptors

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Archives of Dermatology

Volume 136, Issue 5, pp. 609-16

DOI: 10.1001/archderm.136.5.609

Field-Weighted Citation Impact: 4.30