Craniofacial Resection for Malignant Melanoma of the Skull Base

200659 citationsJournal Article

Authors

Ian Ganly · Memorial Sloan Kettering Cancer Center

Snehal G. Patel · Memorial Sloan Kettering Cancer Center

Bhuvanesh Singh · Memorial Sloan Kettering Cancer Center

Dennis H. Kraus · Memorial Sloan Kettering Cancer Center

Patrick G. Bridger

Giulo Cantu · Fondazione IRCCS Istituto Nazionale dei Tumori

Anthony D. Cheesman · Royal National Throat Nose and Ear Hospital

Abstract

Craniofacial resection in patients with malignant melanoma of the skull base has mortality (6%) and complication rates (26%) comparable to other malignant tumors of the skull base. However, malignant melanoma is associated with a much poorer OS, DSS, and RFS. Adjuvant PORT correlated with improved 3-year OS, DSS, and RFS on multivariate analysis. These factors must be taken into account when considering craniofacial resection in a patient with malignant melanoma invading the skull base.

Topics & Keywords

Head and Neck Surgical Oncology Meningioma and schwannoma management Brain Metastases and Treatment

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Archives of Otolaryngology - Head and Neck Surgery

Volume 132, Issue 1, pp. 73-73

DOI: 10.1001/archotol.132.1.73

Field-Weighted Citation Impact: 1.21