Nonactivated versus Thrombin-Activated Platelets on Wound Healing and Fibroblast-to-Myofibroblast Differentiation In Vivo and In Vitro

2011108 citationsJournal Articlegreen Open Access

Authors

Sandra S. Scherer · University of Lausanne

Mickaël Tobalem

Giorgio Pietramaggiori

Abstract

Platelets stimulate wound healing more efficiently compared with activated platelets by enhancing fibroblast differentiation and contractile function. Similar levels of growth factors may induce different biological effects when delivered "on demand" rather than in an initial bolus.

Topics & Keywords

Periodontal Regeneration and Treatments Hemostasis and retained surgical items Electrospun Nanofibers in Biomedical Applications

Publication Details

Published in: Plastic & Reconstructive Surgery

Volume 129, Issue 1, pp. 46e-54e

DOI: 10.1097/prs.0b013e3182362010

Field-Weighted Citation Impact: 5.35

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Nonactivated versus Thrombin-Activated Platelets on Wound Healing and Fibroblast-to-Myofibroblast Differentiation In Vivo and In Vitro

Authors

Abstract

Topics & Keywords

Publication Details