Improved Survival with Bisoprolol in Patients with Heart Failure and Renal Impairment: An Analysis of the Cardiac Insufficiency Bisoprolol Study II (CIBIS-II) Trial

The beneficial effects of bisoprolol on mortality and hospitalization for worsening heart-failure were not modified by baseline eGFR(BSA). Renal impairment should not prevent the use of bisoprolol in patients with HF.