A convenient five‐drug cocktail for the assessment of major drug metabolizing enzymes: a pilot study

200442 citationsJournal Articlebronze Open Access

Authors

Marie Arsenault · Bausch Health (Canada)

Bettina A. Hamelin · Bausch Health (Canada)

Abstract

We propose that this cocktail, composed of five widely available drugs, constitutes a promising means of simultaneously determining the activities of the major CYP enzymes in large populations.

Topics & Keywords

Pharmacogenetics and Drug Metabolism Drug Transport and Resistance Mechanisms Metabolism and Genetic Disorders

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: British Journal of Clinical Pharmacology

Volume 58, Issue 3, pp. 288-297

DOI: 10.1111/j.1365-2125.2004.02162.x

Field-Weighted Citation Impact: 1.29