Green Tea Polyphenol EGCG Sensing Motif on the 67-kDa Laminin Receptor

201288 citationsJournal Articlegold Open Access

Authors

Yoshinori Fujimura · Kyushu University

Mami Sumida · Fukuoka University

Kaori Sugihara · Fukuoka University

Shuntaro Tsukamoto · Fukuoka University

Kôji Yamada · Fukuoka University

Hirofumi Tachibana · Fukuoka University

Abstract

Overall, our results highlight the nature of the EGCG-67LR interaction and provide novel structural insights into the understanding of 67LR-mediated functions of EGCG, and could aid in the development of potential anti-cancer compounds for chemopreventive or therapeutic uses that can mimic EGCG-67LR interactions.

Topics & Keywords

Tea Polyphenols and Effects Atherosclerosis and Cardiovascular Diseases Inflammatory mediators and NSAID effects

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: PLoS ONE

Volume 7, Issue 5, pp. e37942-e37942

DOI: 10.1371/journal.pone.0037942

Field-Weighted Citation Impact: 4.63