FGF-23 Is a Potent Regulator of Vitamin D Metabolism and Phosphate Homeostasis

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Authors

Takashi Shimada

Hisashi Hasegawa

Y. Yamazaki

Takanori Muto

Rieko Hino

Yasuhiro Takeuchi · The University of Tokyo

Toshiro Fujita · The University of Tokyo

Kazuhiko Nakahara · University of Tokyo Hospital

Seiji Fukumoto · University of Tokyo Hospital

Abstract

FGF-23 regulates NaPi-2a independently of PTH and the serum 1,25(OH)2D level by controlling renal expressions of key enzymes of the vitamin D metabolism. In conclusion, FGF-23 is a potent regulator of phosphate and vitamin D homeostasis.

Topics & Keywords

Parathyroid Disorders and Treatments Vitamin D Research Studies Bone health and treatments

Publication Details

Published in: Journal of Bone and Mineral Research

Volume 19, Issue 3, pp. 429-435

DOI: 10.1359/jbmr.0301264

Field-Weighted Citation Impact: 20.63

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FGF-23 Is a Potent Regulator of Vitamin D Metabolism and Phosphate Homeostasis

Authors

Abstract

Topics & Keywords

Publication Details