Evidence That Human Cardiac Myocytes Divide after Myocardial Infarction

20011,421 citationsJournal Article

Authors

Antonio Paolo Beltrami · New York Medical College

Konrad Urbanek · New York Medical College

Jan Kajstura · New York Medical College

Shaomin Yan · University of Udine

Nicoletta Finato · University of Udine

Rossana Bussani · University of Trieste

Bernardo Nadal‐Ginard ·

Abstract

Our results challenge the dogma that the adult heart is a postmitotic organ and indicate that the regeneration of myocytes may be a critical component of the increase in muscle mass of the myocardium.

Topics & Keywords

RNA Research and Splicing Cardiomyopathy and Myosin Studies Muscle Physiology and Disorders

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 344, Issue 23, pp. 1750-1757

DOI: 10.1056/nejm200106073442303

Field-Weighted Citation Impact: 33.77