Reciprocal Metabolic Perturbations in the Adipose Tissue and Liver of GPIHBP1-Deficient Mice

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Authors

Michael M. Weinstein · Tethys Research (United States)

Chris N. Goulbourne · Tethys Research (United States)

Brandon S.J. Davies · Tethys Research (United States)

Yiping Tu · Tethys Research (United States)

Richard H. Barnes · Tethys Research (United States)

Steven M. Watkins · Tethys Research (United States)

Ryan M. Davis

Abstract

Defective lipolysis in Gpihbp1-/- mice causes reciprocal metabolic perturbations in adipose tissue and liver. In adipose tissue, the essential fatty acid content of triglycerides is reduced and lipid biosynthetic gene expression is increased, whereas the opposite changes occur in the liver.

Topics & Keywords

Lipid metabolism and disorders Diabetes and associated disorders Diabetes, Cardiovascular Risks, and Lipoproteins

Publication Details

Published in: Arteriosclerosis Thrombosis and Vascular Biology

Volume 32, Issue 2, pp. 230-235

DOI: 10.1161/atvbaha.111.241406

Field-Weighted Citation Impact: 2.31

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Reciprocal Metabolic Perturbations in the Adipose Tissue and Liver of GPIHBP1-Deficient Mice

Authors

Abstract

Topics & Keywords

Publication Details