Chronic Baroreflex Activation Effects on Sympathetic Nerve Traffic, Baroreflex Function, and Cardiac Haemodynamics in Heart Failure: A Proof-of-Concept Study

BAT was safe and provided chronic improvement in MSNA and clinical variables. Based on present understanding of HF pathophysiology, these results suggest that BAT may improve outcome in HF by modulating autonomic balance. Prospective, randomized trials to test the hypothesis are warranted.