Heme Oxygenase-1 Induction Attenuates Corneal Inflammation and Accelerates Wound Healing after Epithelial Injury

200872 citationsJournal Articlehybrid Open Access

Authors

Kiran Patil

Lars Bellner

Giuseppe Cullaro

Katherine Gotlinger

Michael W. Dunn · New York Medical College

Michal L. Schwartzman

Abstract

Increased expression of HO-1 provides a mechanism that modulates inflammation and promotes wound closure; pharmacologic amplification of this system may constitute a novel strategy to treat corneal inflammation while accelerating wound repair after injury.

Topics & Keywords

Heme Oxygenase-1 and Carbon Monoxide Thermal Regulation in Medicine Burn Injury Management and Outcomes

UN Sustainable Development Goals

Clean water and sanitation

Publication Details

Published in: Investigative Ophthalmology & Visual Science

Volume 49, Issue 8, pp. 3379-3379

DOI: 10.1167/iovs.07-1515

Field-Weighted Citation Impact: 3.23