A panel of five circulating microRNAs as potential biomarkers for prostate cancer

2012183 citationsJournal Articlebronze Open Access

Authors

Zhanghui Chen · Zhejiang Academy of Medical Sciences

G.X. Zhang · State Key Laboratory of Diagnosis and Treatment of Infectious Diseases

Huan‐Rong Li · First Affiliated Hospital Zhejiang University

Jin‐Dan Luo · First Affiliated Hospital Zhejiang University

Zhongxiang Li · Zhejiang Academy of Medical Sciences

Ge-ming Chen · First Affiliated Hospital Zhejiang University

Abstract

Our data suggested that circulating miRNAs could serve as biomarkers for CaP, and compared to single miRNA, the 5 miRNAs panel can accurately discriminate CaP from BPH and healthy controls with high sensitivity and specificity, and therefore, combined with routine PSA test, these 5 CaP-specific miRNAs may help improve CaP diagnosis in clinical application.

Topics & Keywords

MicroRNA in disease regulation Cancer-related molecular mechanisms research Circular RNAs in diseases

UN Sustainable Development Goals

Reduced inequalities

Publication Details

Published in: The Prostate

Volume 72, Issue 13, pp. 1443-1452

DOI: 10.1002/pros.22495

Field-Weighted Citation Impact: 7.26