Weak or no association of TCF7L2 variants with Type 2 diabetes risk in an Arab population

200875 citationsJournal Articlegold Open Access

Authors

Osama Alsmadi · King Faisal Specialist Hospital & Research Centre

Khalid Al‐Rubeaan · King Abdulaziz University

Gamal Mohamed · King Faisal Specialist Hospital & Research Centre

Fadi Alkayal · King Faisal Specialist Hospital & Research Centre

Haya Al‐Saud · King Faisal Specialist Hospital & Research Centre

Nouran Abu Al‐Saud · King Faisal Specialist Hospital & Research Centre

Abstract

Our study is consistent with weak or no association of T2D in Arabs with the two TCF7L2 variants, however it cannot rule out an effect of other SNPs in this gene. Future studies in this population are required to confirm our findings and may indicate the presence of yet to be defined genetic risk factors for T2D.

Topics & Keywords

Genetics and Neurodevelopmental Disorders RNA modifications and cancer Genetic Associations and Epidemiology

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: BMC Medical Genetics

Volume 9, Issue 1, pp. 72-72

DOI: 10.1186/1471-2350-9-72

Field-Weighted Citation Impact: 2.29