A Simple Catalytic Method for the Conversion of Aryl Bromides to Arylamines

19951,024 citationsJournal Article

Authors

Anil S. Guram · Massachusetts Institute of Technology

Roger A. Rennels · Massachusetts Institute of Technology

Stephen L. Buchwald · Massachusetts Institute of Technology

Abstract

A facile Pd-catalyzed method for the preparation of a wide variety of aryl amines from aryl bromides and amines has been developed [Eq. (a)]. Noteworthy features of this method include the experimental simplicity, the tin/boron-free conditions, and the broad spectrum of potential substrates.

Topics & Keywords

Catalytic Cross-Coupling Reactions Catalytic C–H Functionalization Methods Chemical Synthesis and Reactions

Publication Details

Published in: Angewandte Chemie International Edition in English

Volume 34, Issue 12, pp. 1348-1350

DOI: 10.1002/anie.199513481

Field-Weighted Citation Impact: 28.77

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A Simple Catalytic Method for the Conversion of Aryl Bromides to Arylamines

Authors

Abstract

Topics & Keywords

Publication Details