Unusual brain growth patterns in early life in patients with autistic disorder

20011,491 citationsJournal Article

Authors

Eric Courchesne · Center for Neurosciences

Christina M. Karns · Center for Neurosciences

Harvey Davis · Center for Neurosciences

R. Ziccardi · Center for Neurosciences

Ruth A. Carper · Center for Neurosciences

Zachary Tigue · Center for Neurosciences

Heather J. Chisum ·

Abstract

Abnormal regulation of brain growth in autism results in early overgrowth followed by abnormally slowed growth. Hyperplasia was present in cerebral gray matter and cerebral and cerebellar white matter in early life in patients with autism.

Topics & Keywords

Autism Spectrum Disorder Research Genetics and Neurodevelopmental Disorders Congenital heart defects research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Neurology

Volume 57, Issue 2, pp. 245-254

DOI: 10.1212/wnl.57.2.245

Field-Weighted Citation Impact: 18.57