Human Mesenteric Adipose Tissue Plays Unique Role Versus Subcutaneous and Omental Fat in Obesity Related Diabetes

2008101 citationsJournal Article

Authors

Yingkui Yang · University of Alabama at Birmingham

Min Chen · University of Alabama at Birmingham

Ronald H. Clements · University of Alabama at Birmingham

Gary A. Abrams · University of Alabama at Birmingham

Charles J. Aprahamian · University of Alabama at Birmingham

Carroll M. Harmon

Abstract

Human mesenteric adipose tissue in obese diabetic subjects has high basal glycerol release and impaired isoproterenol stimulated glycerol release. The obesity-related gene expressions in the mesenteric adipose tissue are up regulated, suggesting that the alterations of these genes in mesentery adipose depot may play a critical role in insulin resistance of type 2 diabetes and metabolic syndrome.

Topics & Keywords

Adipokines, Inflammation, and Metabolic Diseases Adipose Tissue and Metabolism Cardiovascular Disease and Adiposity

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Cellular Physiology and Biochemistry

Volume 22, Issue 5-6, pp. 531-538

DOI: 10.1159/000185527

Field-Weighted Citation Impact: 2.94

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