Assessment of Pharmacological Treatment of Myocardial Infarction by Phosphorus-31 NMR with Surface Coils

1981136 citationsJournal Article

Authors

Ray L. Nunnally · The University of Texas Southwestern Medical Center

Paul A. Bottomley · General Electric (Israel)

Abstract

Phosphorus-31 nuclear magnetic resonance (NMR) measurements with small surface coils have been used to observe phosphorus metabolism of perfused hearts within localized regions. The method allows for direct, noninvasive, sequential assessment of the altered regional metabolism resulting from myocardial infarction and its response to drug treatment, which cannot be observed by conventional techniques.

Topics & Keywords

Advanced MRI Techniques and Applications Advanced NMR Techniques and Applications Lanthanide and Transition Metal Complexes

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Science

Volume 211, Issue 4478, pp. 177-180

DOI: 10.1126/science.7444460

Field-Weighted Citation Impact: 13.45