Expression analysis of E-cadherin, Slug and GSK3β in invasive ductal carcinoma of breast

2009117 citationsJournal Articlegold Open Access

Authors

Chandra Prakash Prasad · All India Institute of Medical Sciences

Gayatri Rath · Vardhman Mahavir Medical College & Safdarjung Hospital

Sandeep Mathur · All India Institute of Medical Sciences

Dinesh Bhatnagar · Vardhman Mahavir Medical College & Safdarjung Hospital

Rajinder Parshad · All India Institute of Medical Sciences

Ranju Ralhan · All India Institute of Medical Sciences

Abstract

The present study for the first time provided the clinical evidence in support of Wnt/beta-catenin signaling upregulation in IDCs and key components of this pathway - E-cadherin, Slug and GSK3beta with beta-catenin in implementing EMT in these cells.

Topics & Keywords

Hedgehog Signaling Pathway Studies Wnt/β-catenin signaling in development and cancer Epigenetics and DNA Methylation

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: BMC Cancer

Volume 9, Issue 1, pp. 325-325

DOI: 10.1186/1471-2407-9-325

Field-Weighted Citation Impact: 4.70