Sex Differences of Endogenous Sex Hormones and Risk of Type 2 Diabetes

20061,335 citationsReview

Authors

Yiqing Song · American Medical Association

Vasanti Malik · University of California, Los Angeles

Abstract

This systematic review indicates that endogenous sex hormones may differentially modulate glycemic status and risk of type 2 diabetes in men and women. High testosterone levels are associated with higher risk of type 2 diabetes in women but with lower risk in men; the inverse association of SHBG with risk was stronger in women than in men.

Topics & Keywords

Hormonal and reproductive studies Pharmacology and Obesity Treatment Hypothalamic control of reproductive hormones

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JAMA

Volume 295, Issue 11, pp. 1288-1288

DOI: 10.1001/jama.295.11.1288

Field-Weighted Citation Impact: 29.04