Comparing influenza vaccine efficacy against mismatched and matched strains: a systematic review and meta-analysis

2013390 citationsReviewgold Open Access

Authors

Andrea C. Tricco · St. Michael's Hospital

Ayman Chit · University of Toronto

Charlene Soobiah · St. Michael's Hospital

David Hallett · University of Toronto

Genevieve Meier · GlaxoSmithKline (United States)

Maggie H Chen · St. Michael's Hospital

Mariam Tashkandi ·

Abstract

The TIV and LAIV vaccines can provide cross protection against non-matching circulating strains. The point estimates for VE were different for matching versus non-matching strains, with overlapping CIs.

Topics & Keywords

Influenza Virus Research Studies Respiratory viral infections research Bacterial Infections and Vaccines

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: BMC Medicine

Volume 11, Issue 1, pp. 153-153

DOI: 10.1186/1741-7015-11-153

Field-Weighted Citation Impact: 19.34