Interleukin-8 is increased in cerebrospinal fluid of children with severe head injury

2000175 citationsJournal Article

Authors

Michael J. Whalen · Charles R. Drew University of Medicine and Science

Timothy M. Carlos · Charles R. Drew University of Medicine and Science

Patrick M. Kochanek · Charles R. Drew University of Medicine and Science

Stephen R. Wisniewski · Charles R. Drew University of Medicine and Science

Michael J. Bell · Charles R. Drew University of Medicine and Science

Robert S. B. Clark · Charles R. Drew University of Medicine and Science

Abstract

The data are consistent with an acute inflammatory component of TBI in children and suggest an association between cerebrospinal fluid IL-8 and outcome after TBI. IL-8 may represent a potential target for anti-inflammatory therapy.

Topics & Keywords

Neonatal Respiratory Health Research Traumatic Brain Injury and Neurovascular Disturbances S100 Proteins and Annexins

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Critical Care Medicine

Volume 28, Issue 4, pp. 929-934

DOI: 10.1097/00003246-200004000-00003

Field-Weighted Citation Impact: 10.80