Phase 2 Reentry as a Trigger to Initiate Ventricular Fibrillation During Early Acute Myocardial Ischemia

2004155 citationsJournal Article

Authors

Gan‐Xin Yan · First Affiliated Hospital of Xi'an Jiaotong University

Ajay Joshi · First Affiliated Hospital of Xi'an Jiaotong University

Donglin Guo · First Affiliated Hospital of Xi'an Jiaotong University

Thinn Hlaing · First Hospital of Xi'an

J. M. E. Martin · First Affiliated Hospital of Xi'an Jiaotong University

Xiaoping Xu · First Affiliated Hospital of Xi'an Jiaotong University

Abstract

Acute regional myocardial ischemia results in markedly heterogeneous loss of I(to)-mediated epicardial AP domes across the ischemic border, leading to phase 2 reentry. Phase 2 reentry can in turn produce an R-on-T extrasystole capable of initiating VF.

Topics & Keywords

Cardiac electrophysiology and arrhythmias Cardiac Arrhythmias and Treatments Cardiac pacing and defibrillation studies

Publication Details

Published in: Circulation

Volume 110, Issue 9, pp. 1036-1041

DOI: 10.1161/01.cir.0000140258.09964.19

Field-Weighted Citation Impact: 4.23

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Phase 2 Reentry as a Trigger to Initiate Ventricular Fibrillation During Early Acute Myocardial Ischemia

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Abstract

Topics & Keywords

Publication Details