Noninvasive Visualization of the Activated αvβ3 Integrin in Cancer Patients by Positron Emission Tomography and [18F]Galacto-RGD

2005482 citationsJournal Articlegold Open Access

Authors

Roland Haubner · Klinik und Poliklinik für Nuklearmedizin

Wolfgang Weber · Klinik und Poliklinik für Nuklearmedizin

Ambros J. Beer · Technical University of Munich

Eugenija Vabulienė · Technical University of Munich

Daniel Reim · Technical University of Munich

Mario Sarbia · Technical University of Munich

Karl‐Friedrich Becker

Abstract

Molecular imaging with [(18)F]Galacto-RGD and PET can provide important information for planning and monitoring anti-angiogenic therapies targeting the alphavbeta3 integrins and can reveal the involvement and role of this integrin in metastatic and angiogenic processes in various diseases.

Topics & Keywords

Cell Adhesion Molecules Research Platelet Disorders and Treatments Caveolin-1 and cellular processes

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: PLoS Medicine

Volume 2, Issue 3, pp. e70-e70

DOI: 10.1371/journal.pmed.0020070

Field-Weighted Citation Impact: 15.13