Experimental Morphine Addiction: Method for Automatic Intravenous Injections in Unrestrained Rats

1962652 citationsJournal Article

Authors

James R. Weeks · W.E. Upjohn Institute for Employment Research

Abstract

An operant behavioral study on morphine addiction utilized a self-injection technique for giving intravenous injections to relatively unrestrained rats. The rate of self-injection varied inversely with the dose. Morphine was a reinforcer that produced almost immediate satiation.

Topics & Keywords

Neurotransmitter Receptor Influence on Behavior Neuroscience and Neuropharmacology Research Stress Responses and Cortisol

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Science

Volume 138, Issue 3537, pp. 143-144

DOI: 10.1126/science.138.3537.143

Field-Weighted Citation Impact: 2.57