Effect of rhPDGF‐BB on bone turnover during periodontal repair

200699 citationsJournal Articlegreen Open Access

Authors

David P. Sarment · University of Michigan–Ann Arbor

Jason Cooke · University of Michigan–Ann Arbor

Sarah E. Miller · University of Michigan–Ann Arbor

Qiming Jin · University of Michigan–Ann Arbor

Shelley McGuire · Perio Health Professionals

Richard T. Kao

Pamela K. McClain

Bradley S. McAllister

Abstract

This study corroborates the release of ICTP as a measure of active bone turnover following local delivery of PDGF-BB to periodontal osseous defects. The amount of ICTP released from the WF revealed an early increase for all treatment groups. Data from this study suggests that when PDGF-BB is delivered to promote periodontal tissue engineering of tooth-supporting osseous defects, there is a direct effect on ICTP released from the wound.

Topics & Keywords

Periodontal Regeneration and Treatments Oral microbiology and periodontitis research Dental Radiography and Imaging

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal Of Clinical Periodontology

Volume 33, Issue 2, pp. 135-140

DOI: 10.1111/j.1600-051x.2005.00870.x

Field-Weighted Citation Impact: 6.17