Purification of γ-Benzyl and γ-Methyl L-Glutamate N-Carboxyanhydrides by Rephosgenation

199249 citationsJournal Article

Authors

Linneaus C. Dorman · Dow Chemical (United States)

William R. Shiang · Dow Chemical (United States)

Abstract

Abstract Rephosgenation of N-carboxyanhydrides of γ-benzyl and y-methyl L-glutamates, vs multiple recrystallizations, is a very efficient method for obtaining highly purified N-carboxyanhydrides, from which very high MW (0.98-1.5 × 106 Daltons) polymers can be derived.

Topics & Keywords

Chemical Synthesis and Analysis Analytical Chemistry and Chromatography Crystallography and molecular interactions

UN Sustainable Development Goals

Clean water and sanitation

Publication Details

Published in: Synthetic Communications

Volume 22, Issue 22, pp. 3257-3262

DOI: 10.1080/00397919208021140

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