Effect of reproductive factors and postmenopausal hormone use on the risk of Parkinson disease

2005123 citationsJournal Article

Authors

Rita A. Popat · Kaiser Permanente Santa Rosa Medical Center

Stephen K. Van Den Eeden · Kaiser Permanente Santa Rosa Medical Center

Caroline M. Tanner · Kaiser Permanente Santa Rosa Medical Center

V. McGuire · Kaiser Permanente Santa Rosa Medical Center

Allan Bernstein · Kaiser Permanente Santa Rosa Medical Center

D A Bloch · Kaiser Permanente Santa Rosa Medical Center

Amethyst Leimpeter

Abstract

Postmenopausal use of estrogen alone may increase the risk of Parkinson disease (PD) among women with a hysterectomy. Among women with natural menopause for whom the usual treatment is combined estrogen-progestin therapy, no increased risk of PD was observed.

Topics & Keywords

Parkinson's Disease Mechanisms and Treatments Menopause: Health Impacts and Treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Neurology

Volume 65, Issue 3, pp. 383-390

DOI: 10.1212/01.wnl.0000171344.87802.94

Field-Weighted Citation Impact: 4.78