The Risk of Major Birth Defects after Intracytoplasmic Sperm Injection and in Vitro Fertilization

20021,082 citationsJournal Articlebronze Open Access

Authors

Michèle Hansen · The Kids Research Institute Australia

Jennifer J. Kurinczuk · University of Leicester

Carol Bower · The Kids Research Institute Australia

Sandra Webb · Government of Western Australia Department of Health

Abstract

Infants conceived with use of intracytoplasmic sperm injection or in vitro fertilization have twice as high a risk of a major birth defect as naturally conceived infants.

Topics & Keywords

Assisted Reproductive Technology and Twin Pregnancy Prenatal Screening and Diagnostics Reproductive Health and Technologies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 346, Issue 10, pp. 725-730

DOI: 10.1056/nejmoa010035

Field-Weighted Citation Impact: 128.23