Chemotherapy Sensitivity and Resistance Assays: A Systematic Review

2004129 citationsReview

Authors

David J Samson · Blue Cross Blue Shield Association

Jerome Seidenfeld · Blue Cross Blue Shield Association

Kathleen M Ziegler · Blue Cross Blue Shield Association

Naomi Aronson · Blue Cross Blue Shield Association

Abstract

While higher response rates for assay-guided therapy have been observed, differences may be attributable to bias or confounding. Little evidence on survival is available. These results do not establish the relative effectiveness of assay-guided treatment and empiric treatment. Randomized trials are needed.

Topics & Keywords

Statistical Methods in Clinical Trials Lymphoma Diagnosis and Treatment Cancer Genomics and Diagnostics

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Clinical Oncology

Volume 22, Issue 17, pp. 3618-3630

DOI: 10.1200/jco.2004.04.077

Field-Weighted Citation Impact: 9.66