The Mechanical Properties of Hydroxypropylmethylcellulose Films Derived from Aqueous Systems Part 1: The Influence of Plasticisers

The aim of this work is to examine the effects that certain plasticisers have on the properties of aqueous based hydroxypropylmethylcellulose (HPMC) films of a type used for film coating tablets, and to investigate whether or not the inclusion of these additives is in fact beneficial in all cases.The film former HPMC is being used increasingly as a coating for pharmaceutical tablets because of its suitable properties, not least of which is the ability to coat using a fully aqueous system. This greatly improves the method and safety of application.