Effects of Maternal Screening and Universal Immunization to Prevent Mother-to-Infant Transmission of HBV

2011254 citationsJournal Articlehybrid Open Access

Authors

Huey‐Ling Chen · National Taiwan University Hospital

Lung‐Huang Lin · China Medical University

Fu‐Chang Hu · National Taiwan University Hospital

Jian–Te Lee · National Taiwan University Hospital

Wen–Terng Lin · En Chu Kong Hospital

Yao–Jung Yang · National Cheng Kung University Hospital

Fu‐Chen Huang

Abstract

Children born to HBeAg-positive mothers are at greatest risk for chronic HBV infection (9.26%), despite immunization. Administration of HBIG to infants born to HBeAg-negative mothers did not appear to reduce the rate of chronic HBV infection, but might prevent infantile fulminant hepatitis. Screening pregnant women for HBsAg and HBeAg might control mother-to-infant transmission of HBV.

Topics & Keywords

Hepatitis B Virus Studies Hepatitis Viruses Studies and Epidemiology Hepatitis C virus research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Gastroenterology

Volume 142, Issue 4, pp. 773-781.e2

DOI: 10.1053/j.gastro.2011.12.035

Field-Weighted Citation Impact: 11.37