Circulating MiR-125b as a Marker Predicting Chemoresistance in Breast Cancer

2012271 citationsJournal Articlegold Open Access

Authors

Hongjiang Wang · Dalian Medical University

Guang Tan · Dalian Medical University

Lei Dong · Dalian Medical University

Lei Cheng · First Affiliated Hospital of Dalian Medical University

Kejun Li · First Affiliated Hospital of Dalian Medical University

Zhongyu Wang · Dalian Medical University

Haifeng Luo

Abstract

These data suggest that circulating miR-125b expression is associated with chemotherapeutic resistance of breast cancer. This finding has important implications in the development of targeted therapeutics for overcoming chemotherapeutic resistance in novel anti-cancer strategies.

Topics & Keywords

MicroRNA in disease regulation RNA Interference and Gene Delivery Circular RNAs in diseases

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: PLoS ONE

Volume 7, Issue 4, pp. e34210-e34210

DOI: 10.1371/journal.pone.0034210

Field-Weighted Citation Impact: 13.19