Prophylactic Surgery to Reduce the Risk of Gynecologic Cancers in the Lynch Syndrome

2006789 citationsJournal Articlebronze Open Access

Authors

Kathleen M. Schmeler

Henry T. Lynch

Lee-may Chen · The University of Texas MD Anderson Cancer Center

Mark F. Munsell · Applied Mathematics (United States)

Pamela T. Soliman

Mary Beth Clark

Molly S. Daniels · Cancer Genetics (United States)

Kristin G. White

Stephanie Boyd-Rogers

Peggy Conrad

Abstract

These findings suggest that prophylactic hysterectomy with bilateral salpingo-oophorectomy is an effective strategy for preventing endometrial and ovarian cancer in women with the Lynch syndrome.

Topics & Keywords

Genetic factors in colorectal cancer Colorectal Cancer Screening and Detection Colorectal Cancer Surgical Treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 354, Issue 3, pp. 261-269

DOI: 10.1056/nejmoa052627

Field-Weighted Citation Impact: 30.91