Effects of Ablation of the Submaxillary Gland in Guinea Pigs I

1) The nature of the submaxillary gland and the appearance of germ cells in the testis after ablation of the submaxillary gland were studied in guinea pigs.2) In all specimens after operation, the degenerative germ cells were observed in the lobules of testis, whereas the testis did not cause the progressive atrophy, and the renewed spermatogenesis was observed within the prexisting lobules.3) An atrophic change of the germinal cells in the present experiment may be due to androgen affected because of the absence of the submaxillary gland.4) The reciprocal relation between the testis and the submaxillary gland in order to maintain the normal condition of these organs, was observed in this experiment.5) The lack of correlation between the conditions of the testis and the seminal vesicle was observed in the specimen after operation, namely, the germ cells and sperms in the testis suffered damage, whereas the seminal vesicle exhibited normal development.