B7-H1 Expression Is Associated with Poor Prognosis in Colorectal Carcinoma and Regulates the Proliferation and Invasion of HCT116 Colorectal Cancer Cells

2013187 citationsJournal Articlegold Open Access

Authors

Shengjia Shi · Air Force Medical University

Lijuan Wang · First Affiliated Hospital of Xi'an Jiaotong University

Guodong Wang · Chinese People's Liberation Army

Zhangyan Guo · Air Force Medical University

Ming Wei · Air Force Medical University

Yan–Ling Meng · Air Force Medical University

Angang Yang

Abstract

Positive B7-H1 expression is an independent predictor for colorectal carcinoma prognosis. Moreover, knockdown of B7-H1 can inhibit cell proliferation, migration and invasion.

Topics & Keywords

Cancer Immunotherapy and Biomarkers Immunotherapy and Immune Responses Immune Cell Function and Interaction

UN Sustainable Development Goals

No poverty

Publication Details

Published in: PLoS ONE

Volume 8, Issue 10, pp. e76012-e76012

DOI: 10.1371/journal.pone.0076012

Field-Weighted Citation Impact: 6.12