Determination of nucleic acid sequence homologies and relative concentrations by a dot hybridization procedure

19791,395 citationsJournal Articlegreen Open Access

Authors

Argiris Efstratiadis · Harvard University

Abstract

A dot hybridization method is presented for rapidly determining the relative concentrations of nucleic acids in a mixture, as well as the extent of sequence homology between related RNA or DNA species.

Topics & Keywords

DNA and Nucleic Acid Chemistry Advanced biosensing and bioanalysis techniques Molecular Biology Techniques and Applications

Publication Details

Published in: Nucleic Acids Research

Volume 7, Issue 6, pp. 1541-1552

DOI: 10.1093/nar/7.6.1541

Field-Weighted Citation Impact: 19.61

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Determination of nucleic acid sequence homologies and relative concentrations by a dot hybridization procedure

Authors

Abstract

Topics & Keywords

Publication Details