An Open Comparison of Clozapine and Risperidone in Treatment-Resistant Schizophrenia

199851 citationsJournal Article

Authors

Sean P. Flynn · University of British Columbia

G. William MacEwan · Saint-Vincent Hospital

S. Altman · University of British Columbia

Lili C. Kopala · Dalhousie University

Diane Fredrikson · University of British Columbia

G.N. Smith · Riverview Hospital

William G. Honer ·

Abstract

Clozapine had better efficacy in subjects with treatment-resistant schizophrenia compared to risperidone, although risperidone appears to yield better response rates than those previously reported for typical antipsychotics. Double-blind, controlled trials of risperidone are needed to establish its efficacy in treatment-resistant schizophrenia.

Topics & Keywords

Schizophrenia research and treatment Bipolar Disorder and Treatment Treatment of Major Depression

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Pharmacopsychiatry

Volume 31, Issue 01, pp. 25-29

DOI: 10.1055/s-2007-979291

Field-Weighted Citation Impact: 4.87